Showing 5153–5168 of 7558 results

Nateglinide

Nateglinide is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.

Mycophenolic Acid

Mycophenolic acid is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.

Moroxydine HCl

Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.

Mitoxantrone 2HCl

Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively.

Milrinone

Milrinone is a phosphodiesterase 3 (PDE3) inhibitor, used to increase the heart’s contractility.

Manidipine 2HCl

Manidipine 2HCl is a HCl salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4.

Manidipine

Manidipine is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.

Loperamide HCl

Loperamide HCl is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.

Lincomycin HCl

Lincomycin hydrochloride(Lincocin) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.

Itraconazole

Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent.

Imatinib (STI571)

Imatinib (STI571) is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively.

Hexestrol

Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.

Gallamine Triethiodide

Gallamine Triethiodide is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM.

Fluocinolone Acetonide

Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.

Fleroxacin

Fleroxacin is a new broad-spectrum fluoroquinolone.

Fenbendazole

Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.