Showing 2145–2160 of 5738 results
1-Phenyl-1,2-Propanedione
p-Hydroxybenzaldehyde
Bisphenol A
Imidazole
VX-702
VX-702 is a highly selective inhibitor of p38α MAPK, 14-fold higher potency against the p38α versus p38β. Phase 2.
Ataluren (PTC124)
Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.
NXY-059 (Disufenton Sodium)
NXY-059 is a novel nitrone, shows efficacious neuroprotective effects. Phase 3.
Pomaglumetad (LY404039)
LY404039 is a potent agonist of recombinant human mGlu2/mGlu3 receptors with Ki of 149 nM/92 nM, shows >100-fold selectivity over ionotropic glutamate receptors, glutamate transporters, and other receptors. Phase 3.