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The combination of BSTFA and TMCS is the preferred reagent for trimethylsilylation of alcohols, alkaloids, amines, biogenic amines, carboxylic acids, phenols, and steroids. TMCS increases the reactivity of BSTFA. BSTFA-TMCS has good solvent properties and can function as a silylation reagent without additional solvents.
DL-2-Aminoadipic acid is an excitatory amino acid analogue, which functions as a glutamine synthetase inhibitor.
1-Naphthyl phosphate potassium salt is a non-specific phosphatase inhibitor which acts on acid, alkaline, and protein phosphatases.
Berberine sulfate, an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3).
Biphenyl-4-sulfonyl chloride is a HDAC inhibitor with synthetic applications in palladium-catalyzed desulfitative C-arylation.
DDE, a breakdown product of DDT, is an organochlorine pesticide and may behave as a potent androgen receptor antagonist.
2-Hydroxycaprylic acid belongs to the class of organic compounds known as medium-chain fatty acids.
Quinacrine is a dye of the acridine family that has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug.
AS057278 (3-Methylpyrazole-5-carboxylic acid, MPC) is an inhibitor of D-amino acid oxidase (DAAO).
Sodium succinate is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxygen species.
Dibenamine is an irreversible blocker of α1 adrenoceptors.
L-Homoarginine is a specific inhibitor of liver-type alkaline phosphatase.
Metoprolol is a cardioselective β1-adrenergic blocking agent with log Kd values of −7.26±0.07, −6.89±0.09, −5.16±0.12 for β1, β2, and β3 adrenoceptors, respectively. It is used for acute myocardial infarction, heart failure, angina pectoris and mild to moderate hypertension.
Diallyl sulfide, a thioether found naturally in garlic, is a selective inhibitor and also a substrate of CYP2E1 with an IC50 of 17.3 μM. It has protective effects against alcohol- and acetaminophen-induced hepatotoxicity in many studies.
Promazine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.