Bosentan Hydrate
Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
Showing 4193–4208 of 5738 results
Palonosetron HCl
Palonosetron HCl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
Solifenacin Succinate
Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class.
Otilonium Bromide
Otilonium bromide is an antimuscarinic.
Azilsartan
Azilsartan is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.
Cinepazide Maleate
Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.
Lurasidone HCl
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively.
Rofecoxib
Rofecoxib is a COX-2 inhibitor with IC50 of 18 nM.
Purmorphamine
Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM.
Droxidopa
Droxidopa is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).
Fosaprepitant Dimeglumine Salt
Fosaprepitant is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.
Bepotastine Besilate
Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.
Pravastatin Sodium
Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Daunorubicin HCl
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM in a cell-free assay.
Vildagliptin (LAF-237)
Vildagliptin (LAF-237) inhibits DPP−4 with IC50 of 2.3 nM.
Bindarit
Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.