Showing 5169–5184 of 5741 results

Lubiprostone

Lubiprostone is an activator of ClC-2 chloride channels, used in the management of idiopathic chronic constipation.

Aminophylline

Aminophylline is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.

Loteprednol Etabonate

Loteprednol etabonate is a potent glucocorticoid receptor agonist, used in treatment of inflammation of the eye due to allergies.

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Trichlormethiazide

Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide.

Flucytosine

Flucytosine (5-Fluorocytosine, 5-FC) is an antifungal drug with IC50 of 0.93 μM in C. albicans.

Estrone

Estrone is an estrogenic hormone.

Isradipine

Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.

Dofetilide

Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.

Enalaprilat Dihydrate

Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

Ezetimibe

Ezetimibe is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.

Phenylbutazone

Phenylbutazone is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.

Tretinoin

Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

Monobenzone

Monobenzone is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase.

Telbivudine

Telbivudine is a potent, and selective HBV reverse transcriptase inhibitor, used to treat HBV infection.