Showing 5281–5296 of 5741 results

Norfloxacin

Norfloxacin is a broad-spectrum antibiotic.

Alprostadil

Alprostadil is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.

Irbesartan

Irbesartan (SR-47436, BMS-186295) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.

Aztreonam

Aztreonam is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.

Dyphylline

Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.

Cephalexin

Cephalexin is an antibiotic that can treat a number of bacterial infections.

Mycophenolate Mofetil

Mycophenolate Mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively.

Betamethasone

Betamethasone is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.

Cefaclor

Cefaclor is a cephalosporin antibiotic.

NVP-BEP800

NVP-BEP800 is a novel, fully synthetic HSP90β inhibitor with IC50 of 58 nM, exhibits>70-fold selectivity against Hsp90 family members Grp94 and Trap-1.

Pralatrexate

Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.

Ralimetinib (LY2228820)

Ralimetinib (LY2228820) is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, does not alter p38 MAPK activation. Phase 1/2.

Fludarabine

Fludarabine is a STAT1 activation inhibitor which causes a specific depletion of STAT1 protein (and mRNA) but not of other STATs. Also a DNA synthesis inhibitor in vascular smooth muscle cells.

Ponatinib (AP24534)

Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively.

PIK-93

PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM shown to inhibit PI3Kα with IC50 of 39 nM.