IgM and IgG Antibodies
Both IgM and IgG are immunoglobulin which are produced by the immune system to provide protection against the 2019-nCoV. Some patients with negative results in nucleic acid test show positive in IgM test, indicating that the IgG / IgM detection is one of the effective methods for the diagnosis of 2019-nCoV. The level of IgM antibody begins to rise after 1 week after the initial infection, while the IgG appears later than IgM (usually in 14 days after infection) and can last for 6 months or even several years, which means that the IgG serves as an indicator of previous infection. Suspected patients that are infected by 2019-nCoV can be rapidly identified by simultaneous monitoring of IgM and IgG. During the outbreak period of 2003-SARS and the 2016-Zika, IgM / IgG antibody detection was used as one of the recommended diagnostic methods.
Advantages of IgG / IgM Detection
- Indicating both recent infections and previous infections, reducing missed detection rates.
- Low requirements of instruments; suitable for primary hospitals and conventional outpatient clinics.
- Blood testing; low requirements for sampling; no special virus collection tube required.
- Suitable for combined detection with nucleic-acid testing kit to improve the diagnosis rate of suspected patients.
- Rapid-screening within 10 minutes.
- High detection efficiency: simultaneous monitoring of IgM and IgG.
- Detection without any equipments.
- Easy to operate, compatible with serum/whole blood/plasma.
- Room-temperature storage.
Interpreting Test Results
|IgM positive, IgG positive||Indicates that it may be a recent infection with 2019-nCoV.|
|IgM positive, IgG negative||Indicates that it may be a recent infection with 2019-nCoV.|
|IgM negative, IgG positive||Indicates that it may be a previous infection with 2019-nCoV.|
|IgM negative, IgG negative||Indicates that it may be no infection with 2019-nCoV, or there is not enough detectable antibodies in the early infection.|