Anti-Aquaporin-6 (AQP6) (human) antibody is recommended for immunofluorescence labeling, IHC, or western blot of materials from human tissues.
Aquaporin, also known as water channel, mediates water permeation across the cell membrane. There are approximately 10 aquaporin genes in human genome. Aquaporin proteins are composed of six transmembrane domains, three extracellular loops, two intracellular loops and two intracellular termini.
Aquaporin-6 is encoded by the Aqp6 gene in human. Aquaporin-6 is highly expressed by the epithelial tissues including the kidney and the intestines.
This antibody was raised against human specific epitope sequence in Aquaporin-6 protein, which derives from a homologous region to the validated mouse Aquaporin-6 epitope (Cat No.: 20106).