Navitoclax (ABT-263)

117.00 953.00 

Navitoclax (ABT-263) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM in cell-free assays, but binds more weakly to Mcl-1 and A1. Phase 2.

Clear

Additional information

Brand

Selleck Chemicals

CAS No.

923564-51-6

Molecular Weight

974.61

Signaling Pathway

Apoptosis

Target

Bcl-2

Storage

Store at -20°C