Vemurafenib (PLX4032, RG7204)

68.00 756.00 

Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.

Clear

Additional information

Brand

Selleck Chemicals

CAS No.

918504-65-1

Molecular Weight

489.92

Signaling Pathway

MAPK

Target

Raf

Storage

Store at -20°C