{"product_id":"a-1155463-dihydrochloride-s7800","title":"A-1155463 Dihydrochloride","description":"\u003cp\u003e\u003cstrong\u003eA-1155463 Dihydrochloride\u003c\/strong\u003e is an inhibitor of BCL-2 used in studies of Apoptosis. It is especially relevant in apoptosis and cancer models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting BCL-2, A-1155463 Dihydrochloride can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving BCL-2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis and cancer models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, A-1155463 Dihydrochloride is appropriate when a defined chemical perturbant is needed to connect BCL-2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809542709593,"sku":"S7800-5MG","price":154.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809542742361,"sku":"S7800-25MG","price":765.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809542775129,"sku":"S7800-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/S7800-A-1155463-Dihydrochloride-chemical-structure.png?v=1776201871","url":"https:\/\/absource.de\/products\/a-1155463-dihydrochloride-s7800","provider":"Absource Diagnostics","version":"1.0","type":"link"}