{"product_id":"a-779-e0039","title":"A-779","description":"\u003cp\u003e\u003cstrong\u003eA-779\u003c\/strong\u003e is an antagonist of Angiotensin Receptors used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Angiotensin Receptors, A-779 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Angiotensin Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, A-779 is appropriate when a defined chemical perturbant is needed to connect Angiotensin Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804190187865,"sku":"E0039-5MG","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804190220633,"sku":"E0039-25MG","price":285.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e0039-a-779-chemical-structure.gif?v=1776165626","url":"https:\/\/absource.de\/products\/a-779-e0039","provider":"Absource Diagnostics","version":"1.0","type":"link"}