{"product_id":"ac-yvad-cmk-s9727","title":"Ac-YVAD-cmk","description":"\u003cp\u003e\u003cstrong\u003eAc-YVAD-cmk\u003c\/strong\u003e is an inhibitor of Interleukins used in studies of JAK-STAT Signaling and Immune Signaling. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Interleukins, Ac-YVAD-cmk can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Interleukins\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Ac-YVAD-cmk is appropriate when a defined chemical perturbant is needed to connect Interleukins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809743905113,"sku":"S9727-5MG","price":285.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809743937881,"sku":"S9727-25MG","price":855.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809743970649,"sku":"S9727-100MG","price":1936.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s9727-ac-yvad-cmk-chemical-structure.gif?v=1776205217","url":"https:\/\/absource.de\/products\/ac-yvad-cmk-s9727","provider":"Absource Diagnostics","version":"1.0","type":"link"}