{"product_id":"aclacinomycin-a-hydrochloride-e7988","title":"Aclacinomycin A hydrochloride","description":"\u003cp\u003e\u003cstrong\u003eAclacinomycin A hydrochloride\u003c\/strong\u003e is an inhibitor of Topoisomerase and E3 Ligase used in studies of DNA Damage Response and Protein Degradation \/ Proteasome. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation in cancer, cell cycle, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Topoisomerase and E3 Ligase, Aclacinomycin A hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Topoisomerase and E3 Ligase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Protein Degradation \/ Proteasome\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Aclacinomycin A hydrochloride is appropriate when a defined chemical perturbant is needed to connect Topoisomerase and E3 Ligase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Default Title","offer_id":57818711949657,"sku":"E7988","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e7988-aclacinomycin-a-hydrochloride-chemical-structure-tube.png?v=1776276140","url":"https:\/\/absource.de\/products\/aclacinomycin-a-hydrochloride-e7988","provider":"Absource Diagnostics","version":"1.0","type":"link"}