{"product_id":"actinin-alpha-4-actn4-antibody-western-blot-validated","title":"Actinin alpha-4 (ACTN4) Antibody - Western Blot Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eUse this antibody to explore Actinin alpha-4 (ACTN4) when mapping complex behavior and signaling context. Actinin alpha-4 is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol ACTN4.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eShifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution. Kidney disease modeling efforts may include this target when exploring podocyte stress responses and structural change.\u003c\/p\u003e\n\u003cp\u003eInterpreting changes can benefit from separating expression differences from redistribution, particularly when the target cycles between compartments.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eThis denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Actinin alpha-4 so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eChoose the denaturing-format format to study Actinin alpha-4 (ACTN4) in a way that stays anchored to pathway logic.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102437642585,"sku":"00174-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102437675353,"sku":"00174-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102437708121,"sku":"00174-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102437740889,"sku":"00174-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102437773657,"sku":"00174-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102437806425,"sku":"00174-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/actn4-kid-pfa.jpg?v=1779283439","url":"https:\/\/absource.de\/products\/actinin-alpha-4-actn4-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}