{"product_id":"alvimopan-dihydrate-ly246736-dihydrate-s5701","title":"Alvimopan dihydrate (LY246736 dihydrate)","description":"\u003cp\u003e\u003cstrong\u003eAlvimopan dihydrate (LY246736 dihydrate)\u003c\/strong\u003e is an inhibitor of Opioid Receptors used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Opioid Receptors, Alvimopan dihydrate (LY246736 dihydrate) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Opioid Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Alvimopan dihydrate (LY246736 dihydrate) is appropriate when a defined chemical perturbant is needed to connect Opioid Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57809265557849,"sku":"S5701-5MG","price":124.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57809265590617,"sku":"S5701-25MG","price":383.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58478741782873,"sku":"C11266-5MG","price":93.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58478741815641,"sku":"C11266-25MG","price":285.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/alvimopan-dihydrate-chemical-structure-s5701.gif?v=1776198702","url":"https:\/\/absource.de\/products\/alvimopan-dihydrate-ly246736-dihydrate-s5701","provider":"Absource Diagnostics","version":"1.0","type":"link"}