{"product_id":"am251-s2819","title":"AM251","description":"\u003cp\u003e\u003cstrong\u003eAM251\u003c\/strong\u003e is an antagonist of Cannabinoid Receptors used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Cannabinoid Receptors, AM251 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Cannabinoid Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AM251 is appropriate when a defined chemical perturbant is needed to connect Cannabinoid Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805784973657,"sku":"S2819-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805785006425,"sku":"S2819-50MG","price":461.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/AM251-chemical-structure-s2819.gif?v=1776175771","url":"https:\/\/absource.de\/products\/am251-s2819","provider":"Absource Diagnostics","version":"1.0","type":"link"}