{"product_id":"amcenestrant-sar439859-s9609","title":"Amcenestrant (SAR439859)","description":"\u003cp\u003e\u003cstrong\u003eAmcenestrant (SAR439859)\u003c\/strong\u003e is an antagonist of Estrogen\/Progesterone Receptors and Estrogen Receptor used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in cancer and endocrinology models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Estrogen\/Progesterone Receptors and Estrogen Receptor, Amcenestrant (SAR439859) can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Estrogen\/Progesterone Receptors and Estrogen Receptor\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Amcenestrant (SAR439859) is appropriate when a defined chemical perturbant is needed to connect Estrogen\/Progesterone Receptors and Estrogen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809732534617,"sku":"S9609-5MG","price":383.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809732567385,"sku":"S9609-25MG","price":1149.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809732600153,"sku":"S9609-1ML\/DMSO","price":451.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s9609-sar439859-chemical-structure.gif?v=1776205197","url":"https:\/\/absource.de\/products\/amcenestrant-sar439859-s9609","provider":"Absource Diagnostics","version":"1.0","type":"link"}