{"product_id":"andrographolide-s2261","title":"Andrographolide","description":"\u003cp\u003e\u003cstrong\u003eAndrographolide\u003c\/strong\u003e is an inhibitor of NF-kB used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting NF-kB, Andrographolide can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NF-kB\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Andrographolide is appropriate when a defined chemical perturbant is needed to connect NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 50 mg","offer_id":57805483049305,"sku":"S2261-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 200 mg","offer_id":57805483082073,"sku":"S2261-200MG","price":242.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 50 mg","offer_id":58478525546841,"sku":"C08401-50MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 200 mg","offer_id":58478525579609,"sku":"C08401-200MG","price":180.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Andrographolide-chemical-structure-S2261.gif?v=1776174710","url":"https:\/\/absource.de\/products\/andrographolide-s2261","provider":"Absource Diagnostics","version":"1.0","type":"link"}