{"product_id":"anoctamin-1-ano1-or-tmem16a-c-terminus-antibody-ffpe-validated","title":"Anoctamin-1 (ANO1 or TMEM16A) (C-Terminus) Antibody - FFPE Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eThis antibody is suited for researchers who want to explore Anoctamin-1 C-Terminus and relate it to cell-state biology. Anoctamin-1 C-Terminus is a membrane protein linked to solute movement and gradient maintenance. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol ANO1.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eMany transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.\u003c\/p\u003e\n\u003cp\u003eDepending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esurface versus intracellular pool distribution\u003c\/li\u003e\n\u003cli\u003estimulus-dependent trafficking and turnover\u003c\/li\u003e\n\u003cli\u003erelative abundance across engineered constructs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Anoctamin-1 C-Terminus measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section version supports deeper biological narratives around Anoctamin-1 C-Terminus without overcomplicating setup.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101761343833,"sku":"20530-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101761376601,"sku":"20530-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101761409369,"sku":"20530-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101761442137,"sku":"20530-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101761474905,"sku":"20530-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101761507673,"sku":"20530-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/tm16ac-brain-cortex_ca166526-6780-4559-935a-de7d992fa7ac.jpg?v=1779281421","url":"https:\/\/absource.de\/products\/anoctamin-1-ano1-or-tmem16a-c-terminus-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}