{"product_id":"anxa1-antibody-sc-f0876","title":"Annexin A1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eAnnexin A1 (ANXA1), previously known as lipocortin 1, belongs to the vertebrate annexin class A family of proteins. It plays diverse roles in key biological processes such as cell differentiation, proliferation, plasma membrane repair, epithelial repair, and apoptosis. ANXA1 has the ability to bind to negatively charged cellular phospholipids, vesicles, and cytoskeletal proteins like F-actin, suggesting its involvement in intracellular trafficking. Depending on the literature source, ANXA1 may also be discussed as Annexin A1 and Annexin I.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, cell projection, cilium, and cytoplasm, which can matter when signal is compared across treatments or changing cell states. Following ANXA1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eANXA1 is commonly interpreted in the context of immunology and neuroscience research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cell projection, and cilium, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, cell projection, and cilium across matched conditions\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for ANXA1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in ANXA1 reflect biology rather than handling. When interpreting ANXA1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep ANXA1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577544712537,"sku":"F0876-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577544745305,"sku":"F0876-100UL","price":359.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577544778073,"sku":"F0876-2X100UL","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0876-IHC1.jpg?v=1773599042","url":"https:\/\/absource.de\/products\/anxa1-antibody-sc-f0876","provider":"Absource Diagnostics","version":"1.0","type":"link"}