{"product_id":"apt1-antibody-sc-f2816","title":"Lysophospholipase 1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eAPT1 is a target of interest in many antibody-based workflows. Lysophospholipase 1 (LPL-I), also known as LYPLA1, is a cytoplasmic enzyme essential for lipid metabolism, primarily hydrolyzing lysophospholipids (LysoPLs), which are key intermediates in the Lands cycle responsible for phospholipid remodelling and lipid signaling regulation. It adopts an α\/β hydrolase fold with a conserved Ser-His-Asp catalytic triad that enables efficient cleavage of fatty acyl chains from LysoPLs. Depending on the literature source, APT1 may also be discussed as Lysophospholipase 1 and LYPLA1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cellmembrane, cytoplasm, endoplasmicreticulum, and membrane, which can matter when signal is compared across treatments or changing cell states. Following APT1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eAPT1 is commonly interpreted in the context of neuroscience, metabolism, and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cellmembrane, cytoplasm, and endoplasmicreticulum, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cellmembrane, cytoplasm, and endoplasmicreticulum across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for APT1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in APT1 reflect biology rather than handling. When interpreting APT1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep APT1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577973711193,"sku":"F2816-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577973743961,"sku":"F2816-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577973776729,"sku":"F2816-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2816-wb.gif?v=1773600715","url":"https:\/\/absource.de\/products\/apt1-antibody-sc-f2816","provider":"Absource Diagnostics","version":"1.0","type":"link"}