{"product_id":"apto-253-s6963","title":"APTO-253","description":"\u003cp\u003e\u003cstrong\u003eAPTO-253\u003c\/strong\u003e is an inhibitor of MYC used in studies of Cell Cycle Regulation and Apoptosis. In practice, this places the compound in experiments that measure checkpoint control, mitotic progression, and proliferation timing and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell cycle models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting MYC, APTO-253 can be used to examine checkpoint control, mitotic progression, and proliferation timing and caspase-associated cell-death signaling and survival decisions. This context is compatible with cell-cycle, mitotic, and proliferation assays and apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving MYC\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Cell Cycle Regulation and Apoptosis\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis, cancer, and cell cycle models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, APTO-253 is appropriate when a defined chemical perturbant is needed to connect MYC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809443062105,"sku":"S6963-5MG","price":264.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809443094873,"sku":"S6963-25MG","price":793.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809443127641,"sku":"S6963-100MG","price":1982.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s6963-apto-253-chemical-structure.gif?v=1776200747","url":"https:\/\/absource.de\/products\/apto-253-s6963","provider":"Absource Diagnostics","version":"1.0","type":"link"}