{"product_id":"asenapine-maleate-s1283","title":"Asenapine maleate","description":"\u003cp\u003e\u003cstrong\u003eAsenapine maleate\u003c\/strong\u003e is an antagonist of 5-HT Receptors and Histamine Receptors used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in inflammation and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking 5-HT Receptors and Histamine Receptors, Asenapine maleate can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving 5-HT Receptors and Histamine Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling and Neurotransmission\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Asenapine maleate is appropriate when a defined chemical perturbant is needed to connect 5-HT Receptors and Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"25 mg","offer_id":57805264224601,"sku":"S1283-25MG","price":144.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Asenapine-maleate-chemical-structure-S1283.gif?v=1776173282","url":"https:\/\/absource.de\/products\/asenapine-maleate-s1283","provider":"Absource Diagnostics","version":"1.0","type":"link"}