{"product_id":"ataluren-ptc124-s6003","title":"Ataluren (PTC124)","description":"\u003cp\u003e\u003cstrong\u003eAtaluren (PTC124)\u003c\/strong\u003e is an inhibitor of CFTR used in studies of ion-channel pharmacology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ion conductance, membrane potential, and electrophysiological responses in cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting CFTR, Ataluren (PTC124) can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CFTR\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cell signaling models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Ataluren (PTC124) is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809317462361,"sku":"S6003-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809317495129,"sku":"S6003-50MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809317527897,"sku":"S6003-1G","price":1670.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809317560665,"sku":"S6003-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/PTC124-Ataluren-chemical-structure-S6003.gif?v=1776199182","url":"https:\/\/absource.de\/products\/ataluren-ptc124-s6003","provider":"Absource Diagnostics","version":"1.0","type":"link"}