{"product_id":"atamparib-rbn-2397-s8993","title":"Atamparib (RBN-2397)","description":"\u003cp\u003e\u003cstrong\u003eAtamparib (RBN-2397)\u003c\/strong\u003e is an inhibitor of PARP used in studies of DNA Damage Response. It is especially relevant in cancer and dna damage \/ repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PARP, Atamparib (RBN-2397) can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PARP\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Atamparib (RBN-2397) is appropriate when a defined chemical perturbant is needed to connect PARP with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57809677975897,"sku":"S8993-5MG","price":560.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57809678008665,"sku":"S8993-25MG","price":1542.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 100 mg","offer_id":57809678041433,"sku":"S8993-100MG","price":3901.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 ml (10mM\/DMSO)","offer_id":57809678074201,"sku":"S8993-1ML\/DMSO","price":678.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58479082701145,"sku":"C13844-5MG","price":419.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58479082733913,"sku":"C13844-25MG","price":1151.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 100 mg","offer_id":58479082766681,"sku":"C13844-100MG","price":2913.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s8993-rbn-2397-chemical-structure.gif?v=1776204848","url":"https:\/\/absource.de\/products\/atamparib-rbn-2397-s8993","provider":"Absource Diagnostics","version":"1.0","type":"link"}