{"product_id":"ave-0991-e1060","title":"AVE 0991","description":"\u003cp\u003e\u003cstrong\u003eAVE 0991\u003c\/strong\u003e is an agonist of Angiotensin Receptors used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating Angiotensin Receptors, AVE 0991 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Angiotensin Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AVE 0991 is appropriate when a defined chemical perturbant is needed to connect Angiotensin Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804316541273,"sku":"E1060-5MG","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E1060-AVE-0991-chemical-structure.png?v=1776166450","url":"https:\/\/absource.de\/products\/ave-0991-e1060","provider":"Absource Diagnostics","version":"1.0","type":"link"}