{"product_id":"az1495-e2647","title":"AZ1495","description":"\u003cp\u003e\u003cstrong\u003eAZ1495\u003c\/strong\u003e is an inhibitor of Interleukins used in studies of JAK-STAT Signaling and Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Interleukins, AZ1495 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Interleukins\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AZ1495 is appropriate when a defined chemical perturbant is needed to connect Interleukins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804601327961,"sku":"E2647-5MG","price":390.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804601360729,"sku":"E2647-25MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804601393497,"sku":"E2647-100MG","price":1936.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804601426265,"sku":"E2647-1G","price":3921.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e2647-az1495-chemical-structure.gif?v=1776167798","url":"https:\/\/absource.de\/products\/az1495-e2647","provider":"Absource Diagnostics","version":"1.0","type":"link"}