{"product_id":"az6102-s7767","title":"AZ6102","description":"\u003cp\u003e\u003cstrong\u003eAZ6102\u003c\/strong\u003e is an inhibitor of PPAR used in studies of Wnt Signaling and DNA Damage Response and related signaling programs. In practice, this places the compound in experiments that measure beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control in cancer, developmental biology, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PPAR, AZ6102 can be used to examine beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer, developmental biology, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PPAR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Wnt Signaling and DNA Damage Response and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AZ6102 is appropriate when a defined chemical perturbant is needed to connect PPAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, developmental biology, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809539105113,"sku":"S7767-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809539137881,"sku":"S7767-25MG","price":439.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809539170649,"sku":"S7767-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809539203417,"sku":"S7767-1G","price":3921.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809539236185,"sku":"S7767-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/az6102-chemical-structure-s7767.gif?v=1776201825","url":"https:\/\/absource.de\/products\/az6102-s7767","provider":"Absource Diagnostics","version":"1.0","type":"link"}