{"product_id":"azd1208-s7104","title":"AZD1208","description":"\u003cp\u003e\u003cstrong\u003eAZD1208\u003c\/strong\u003e is an inhibitor of PIM used in studies of JAK-STAT Signaling and Cell Cycle Regulation and related signaling programs. It is especially relevant in apoptosis, autophagy, and cancer models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and checkpoint control, mitotic progression, and proliferation timing.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PIM, AZD1208 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PIM\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and Cell Cycle Regulation and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AZD1208 is appropriate when a defined chemical perturbant is needed to connect PIM with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809454432601,"sku":"S7104-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809454465369,"sku":"S7104-50MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809454498137,"sku":"S7104-1G","price":1955.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809454530905,"sku":"S7104-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/AZD1208-chemical-structure-s7104.gif?v=1776200925","url":"https:\/\/absource.de\/products\/azd1208-s7104","provider":"Absource Diagnostics","version":"1.0","type":"link"}