{"product_id":"bavdegalutamide-arv-110-s6965","title":"Bavdegalutamide (ARV-110)","description":"\u003cp\u003e\u003cstrong\u003eBavdegalutamide (ARV-110)\u003c\/strong\u003e is a modulator of Androgen Receptor used in studies of Protein Degradation \/ Proteasome and Hormone Signaling. In practice, this places the compound in experiments that measure ubiquitin-dependent turnover, proteostasis, and targeted protein degradation and ligand-dependent transcriptional programs and endocrine regulation in cancer, endocrinology, and protein homeostasis models.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating Androgen Receptor, Bavdegalutamide (ARV-110) can be used to examine ubiquitin-dependent turnover, proteostasis, and targeted protein degradation and ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer, endocrinology, and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Androgen Receptor\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Protein Degradation \/ Proteasome and Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Bavdegalutamide (ARV-110) is appropriate when a defined chemical perturbant is needed to connect Androgen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, endocrinology, and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809443160409,"sku":"S6965-5MG","price":195.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809443193177,"sku":"S6965-25MG","price":586.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809443225945,"sku":"S6965-100MG","price":1464.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809443258713,"sku":"S6965-1G","price":5867.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s6965-arv-110-chemical-structure.gif?v=1776200749","url":"https:\/\/absource.de\/products\/bavdegalutamide-arv-110-s6965","provider":"Absource Diagnostics","version":"1.0","type":"link"}