{"product_id":"bbs8-ttc8-antibody-ffpe-validated","title":"BBS8 (TTC8) Antibody - FFPE Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eDesigned to help you assess BBS8 (TTC8), this antibody supports studies where protein context matters. BBS8 is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol TTC8.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eDisruption of intraflagellar transport or basal body function can produce distinct localization signatures. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.\u003c\/p\u003e\n\u003cp\u003eWhen cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esignal enrichment at basal bodies versus cytoplasm\u003c\/li\u003e\n\u003cli\u003echanges in cilia incidence or apparent length in perturbation studies\u003c\/li\u003e\n\u003cli\u003ecell-cycle linked differences in localization\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing BBS8 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting BBS8, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eUse the fixed-section variant when your project demands BBS8 (TTC8) readouts that respect preparation constraints.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101360722265,"sku":"90208-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101360755033,"sku":"90208-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101360787801,"sku":"90208-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101360820569,"sku":"90208-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101360853337,"sku":"90208-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101360886105,"sku":"90208-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/bbs8-retina-pfa_1abd9457-eaf1-42f8-87b0-68ea2ce28bf1.jpg?v=1779279354","url":"https:\/\/absource.de\/products\/bbs8-ttc8-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}