{"product_id":"belotecan-ckd-602-hydrochloride-s6631","title":"Belotecan (CKD-602)hydrochloride","description":"\u003cp\u003e\u003cstrong\u003eBelotecan (CKD-602)hydrochloride\u003c\/strong\u003e is an inhibitor of Topoisomerase used in studies of DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control in cancer and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Topoisomerase, Belotecan (CKD-602)hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Topoisomerase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Belotecan (CKD-602)hydrochloride is appropriate when a defined chemical perturbant is needed to connect Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809401413977,"sku":"S6631-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809401446745,"sku":"S6631-25MG","price":449.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/ckd-602-hydrochloride-chemical-structure-s6631.gif?v=1776200208","url":"https:\/\/absource.de\/products\/belotecan-ckd-602-hydrochloride-s6631","provider":"Absource Diagnostics","version":"1.0","type":"link"}