{"product_id":"berberine-chloride-s2271","title":"Berberine chloride","description":"\u003cp\u003e\u003cstrong\u003eBerberine chloride\u003c\/strong\u003e is a modulator of Autophagy and Topoisomerase used in studies of MAPK \/ ERK Signaling and DNA Damage Response and related signaling programs. It is especially relevant in apoptosis, autophagy, and cancer models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating Autophagy and Topoisomerase, Berberine chloride can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control. The autophagy modulator annotation adds relevance to autophagy-flux and lysosomal-response studies, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Autophagy and Topoisomerase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and DNA Damage Response and related signaling programs\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eAutophagy-flux and lysosomal-response studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Berberine chloride is appropriate when a defined chemical perturbant is needed to connect Autophagy and Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805485834585,"sku":"S2271-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805485867353,"sku":"S2271-50MG","price":242.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57805485900121,"sku":"S2271-200MG","price":341.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805485932889,"sku":"S2271-1G","price":855.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/berberine-chloride-chemical-structure-s2271.gif?v=1776174740","url":"https:\/\/absource.de\/products\/berberine-chloride-s2271","provider":"Absource Diagnostics","version":"1.0","type":"link"}