{"product_id":"betulinic-acid-s3603","title":"Betulinic acid","description":"\u003cp\u003e\u003cstrong\u003eBetulinic acid\u003c\/strong\u003e is an inhibitor of Topoisomerase and NF-kB used in studies of NF-kB Signaling and Immune Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in cancer, dna damage \/ repair, and immunology models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Topoisomerase and NF-kB, Betulinic acid can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage \/ repair, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Topoisomerase and NF-kB\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Betulinic acid is appropriate when a defined chemical perturbant is needed to connect Topoisomerase and NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage \/ repair, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57808914809177,"sku":"S3603-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57808914841945,"sku":"S3603-100MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Betulinic-acid-chemical-structure-s3603.jpg?v=1776195096","url":"https:\/\/absource.de\/products\/betulinic-acid-s3603","provider":"Absource Diagnostics","version":"1.0","type":"link"}