{"product_id":"bms-986397-e4725","title":"BMS-986397","description":"\u003cp\u003e\u003cstrong\u003eBMS-986397\u003c\/strong\u003e is a modulator of CK2 used in studies of Protein Degradation \/ Proteasome. It is especially relevant in cancer, cell signaling, and metabolism models, where defined compound exposure can be linked to ubiquitin-dependent turnover, proteostasis, and targeted protein degradation.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating CK2, BMS-986397 can be used to examine ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CK2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Protein Degradation \/ Proteasome\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, BMS-986397 is appropriate when a defined chemical perturbant is needed to connect CK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57804935790937,"sku":"E4725-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57804935823705,"sku":"E4725-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 100 mg","offer_id":57804935856473,"sku":"E4725-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 g","offer_id":57804935889241,"sku":"E4725-1G","price":2918.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58478193148249,"sku":"C03311-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58478193181017,"sku":"C03311-25MG","price":365.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 100 mg","offer_id":58478193213785,"sku":"C03311-100MG","price":712.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 1 g","offer_id":58478193246553,"sku":"C03311-1G","price":2179.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E4725-BMS-986397-chemical-structure.png?v=1776170027","url":"https:\/\/absource.de\/products\/bms-986397-e4725","provider":"Absource Diagnostics","version":"1.0","type":"link"}