{"product_id":"ca199-antibody-sc-f2466","title":"CA19-9 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCA199 is a target of interest in many antibody-based workflows. CA19-9 (Carbohydrate antigen 19-9), also known as Sialyl Lewis A (sLeᵃ), is a sialylated Lewis blood group antigen, a tetrasaccharide glycan epitope composed of sialic acid, galactose, N-acetylglucosamine, and fucose, biosynthesized via the Lewis blood group pathway and requiring a functional Lewis antigen for its formation. CA19-9 is expressed on glycoproteins and glycolipids of epithelial cell membranes, particularly in the pancreas, biliary tract, stomach, and colon, and can be shed into the bloodstream. Depending on the literature source, CA199 may also be discussed as CA19-9 and CA19.9.\u003c\/p\u003e\u003cp\u003eReported cellular context includes c17a13, which can matter when signal is compared across treatments or changing cell states. Following CA199 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCA199 is commonly interpreted in the context of cancer, immunology, and metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans c17a13, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within c17a13 relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CA199. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CA199 reflect biology rather than handling. When interpreting CA199, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CA199 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577953001817,"sku":"F2466-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577953034585,"sku":"F2466-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577953067353,"sku":"F2466-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2466-IHC1.jpg?v=1773600430","url":"https:\/\/absource.de\/products\/ca199-antibody-sc-f2466","provider":"Absource Diagnostics","version":"1.0","type":"link"}