{"product_id":"cay10603-bml-281-s7596","title":"CAY10603 (BML-281)","description":"\u003cp\u003e\u003cstrong\u003eCAY10603 (BML-281)\u003c\/strong\u003e is an inhibitor of HDAC used in studies of DNA Damage Response and Epigenetic Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation in cancer, dna damage \/ repair, and epigenetics models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HDAC, CAY10603 (BML-281) can be used to examine checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage \/ repair, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HDAC\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, CAY10603 (BML-281) is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage \/ repair, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57809499685209,"sku":"S7596-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57809499717977,"sku":"S7596-25MG","price":468.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 100 mg","offer_id":57809499750745,"sku":"S7596-100MG","price":979.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 g","offer_id":57809499783513,"sku":"S7596-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 ml (10mM\/DMSO)","offer_id":57809499816281,"sku":"S7596-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58478909325657,"sku":"C12806-5MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58478909358425,"sku":"C12806-25MG","price":349.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 100 mg","offer_id":58478909391193,"sku":"C12806-100MG","price":731.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 1 g","offer_id":58478909423961,"sku":"C12806-1G","price":2195.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cay10603-chemical-structure-s7596.gif?v=1776201603","url":"https:\/\/absource.de\/products\/cay10603-bml-281-s7596","provider":"Absource Diagnostics","version":"1.0","type":"link"}