{"product_id":"ccg-222740-s6673","title":"CCG-222740","description":"\u003cp\u003e\u003cstrong\u003eCCG-222740\u003c\/strong\u003e is an inhibitor of Rho GTPases used in studies of target-focused biology. In practice, this places the compound in experiments that measure annotated target biology and downstream cellular responses in cancer, cell cycle, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Rho GTPases, CCG-222740 can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Rho GTPases\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer, cell cycle, and cell signaling models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, CCG-222740 is appropriate when a defined chemical perturbant is needed to connect Rho GTPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"2 mg","offer_id":57809406591321,"sku":"S6673-2MG","price":175.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57809406624089,"sku":"S6673-5MG","price":350.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/ccg-222740-chemical-structure-s6673.gif?v=1776200286","url":"https:\/\/absource.de\/products\/ccg-222740-s6673","provider":"Absource Diagnostics","version":"1.0","type":"link"}