{"product_id":"cd103-antibody-sc-f2447","title":"CD103 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCD103, also known as integrin αEβ7, is a key surface marker with critical functions in the immune system. This integrin is predominantly expressed on tissue-resident T cells and dendritic cells (DCs), where it supports their adhesion and retention within epithelial tissues, such as those in the gut and skin. Depending on the literature source, CD103 may also be discussed as CD103 (Integrin alpha E).\u003c\/p\u003e\u003cp\u003eReported cellular context includes membrane, which can matter when signal is compared across treatments or changing cell states. Following CD103 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCD103 is commonly interpreted in the context of immunology and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within membrane relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CD103. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CD103 reflect biology rather than handling. When interpreting CD103, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CD103 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577945923929,"sku":"F2447-20UL","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577945956697,"sku":"F2447-100UL","price":349.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577945989465,"sku":"F2447-2X100UL","price":559.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2447-wb.gif?v=1773600410","url":"https:\/\/absource.de\/products\/cd103-antibody-sc-f2447","provider":"Absource Diagnostics","version":"1.0","type":"link"}