{"product_id":"cftrinh-172-s7139","title":"CFTRinh-172","description":"\u003cp\u003e\u003cstrong\u003eCFTRinh-172\u003c\/strong\u003e is an inhibitor of CFTR used in studies of ion-channel pharmacology. It is especially relevant in cell signaling models, where defined compound exposure can be linked to ion conductance, membrane potential, and electrophysiological responses. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting CFTR, CFTRinh-172 can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CFTR\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cell signaling models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, CFTRinh-172 is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809457643865,"sku":"S7139-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809457676633,"sku":"S7139-50MG","price":461.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809457709401,"sku":"S7139-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809457742169,"sku":"S7139-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/CFTRinh-172-chemical-structure-s7139.gif?v=1776200982","url":"https:\/\/absource.de\/products\/cftrinh-172-s7139","provider":"Absource Diagnostics","version":"1.0","type":"link"}