{"product_id":"chloroquine-diphosphate-s4157","title":"Chloroquine diphosphate","description":"\u003cp\u003e\u003cstrong\u003eChloroquine diphosphate\u003c\/strong\u003e is an activator of ATM and Autophagy and related targets used in studies of DNA Damage Response and Autophagy. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control and autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating ATM and Autophagy and related targets, Chloroquine diphosphate can be used to examine checkpoint activation, DNA repair, and genome-stability control and autophagic flux, lysosomal turnover, and stress adaptation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ATM and Autophagy and related targets\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Autophagy\u003c\/li\u003e\n\u003cli\u003eGain-of-function pathway-activation studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Chloroquine diphosphate is appropriate when a defined chemical perturbant is needed to connect ATM and Autophagy and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 50 mg","offer_id":57809003544921,"sku":"S4157-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 200 mg","offer_id":57809003577689,"sku":"S4157-200MG","price":265.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 50 mg","offer_id":58478658158937,"sku":"C09965-50MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 200 mg","offer_id":58478658191705,"sku":"C09965-200MG","price":199.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/chloroquine-phosphate-chemical-structure-s4157.gif?v=1776196100","url":"https:\/\/absource.de\/products\/chloroquine-diphosphate-s4157","provider":"Absource Diagnostics","version":"1.0","type":"link"}