{"product_id":"chroman-1-e1261","title":"Chroman 1","description":"\u003cp\u003e\u003cstrong\u003eChroman 1\u003c\/strong\u003e is an inhibitor of ROCK used in studies of kinase signaling. It is especially relevant in cancer, cardiovascular, and cell cycle models, where defined compound exposure can be linked to phosphorylation signaling, target engagement, and selectivity relationships.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting ROCK, Chroman 1 can be used to examine phosphorylation signaling, target engagement, and selectivity relationships. This target class is commonly examined through biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping. In cancer, cardiovascular, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ROCK\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer, cardiovascular, and cell cycle models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Chroman 1 is appropriate when a defined chemical perturbant is needed to connect ROCK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804370313561,"sku":"E1261-5MG","price":274.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804370346329,"sku":"E1261-25MG","price":822.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1261-Chroman-1-chemical-structure.png?v=1776166722","url":"https:\/\/absource.de\/products\/chroman-1-e1261","provider":"Absource Diagnostics","version":"1.0","type":"link"}