{"product_id":"cilengitide-emd-121974-s6387","title":"Cilengitide (EMD 121974)","description":"\u003cp\u003e\u003cstrong\u003eCilengitide (EMD 121974)\u003c\/strong\u003e is an inhibitor of Integrins used in studies of target-focused biology. It is especially relevant in angiogenesis and cancer models, where defined compound exposure can be linked to annotated target biology and downstream cellular responses.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Integrins, Cilengitide (EMD 121974) can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In angiogenesis and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Integrins\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in angiogenesis and cancer models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Cilengitide (EMD 121974) is appropriate when a defined chemical perturbant is needed to connect Integrins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809372840281,"sku":"S6387-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809372873049,"sku":"S6387-25MG","price":409.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809372905817,"sku":"S6387-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809372938585,"sku":"S6387-1G","price":3921.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809372971353,"sku":"S6387-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s6387-cilengitide-chemical-structure.gif?v=1776199758","url":"https:\/\/absource.de\/products\/cilengitide-emd-121974-s6387","provider":"Absource Diagnostics","version":"1.0","type":"link"}