{"product_id":"clathrin-heavy-chain-cltc-hire-antibody-western-blot-validated","title":"Clathrin Heavy Chain (CLTC) HiRe Antibody - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003ePlan your comparisons around Clathrin Heavy Chain (CLTC) and use this antibody to investigate state-dependent differences. Clathrin Heavy Chain is a scaffold that can coordinate signaling with cytoskeletal remodeling. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol CLTC.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eComparative analysis across confluence states can reveal junctional coupling or stress-fiber reorganization. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eMany workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies. Endocytosis-focused experiments may assess how this target traffics between membrane and internal compartments.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003estress-fiber versus cortical distribution patterns\u003c\/li\u003e\n\u003cli\u003eremodeling after perturbation of polymerization or contractility\u003c\/li\u003e\n\u003cli\u003eassociation with junctional complexes or focal adhesions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eWhen samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Clathrin Heavy Chain so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eThe denaturing-format format fits designs where Clathrin Heavy Chain (CLTC) is evaluated with deliberate controls and careful comparisons.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101693022553,"sku":"31060-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101693055321,"sku":"31060-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101693088089,"sku":"31060-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101693120857,"sku":"31060-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101693153625,"sku":"31060-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101693186393,"sku":"31060-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/human-rpe1-cells-labeled-with-clathrin-heavy-chain-cltc-antibody-4096x2304-2.png?v=1779281090","url":"https:\/\/absource.de\/products\/clathrin-heavy-chain-cltc-hire-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}