{"product_id":"claudin-1-cldn1-antibody-ffpe-validated","title":"Claudin-1 (CLDN1) Antibody - FFPE Validated","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\n\u003cp\u003eThis antibody supports experimental designs that assess Claudin-1 with interpretable controls and clear contrasts. Claudin-1 is a membrane-associated component that helps organize cell-cell contacts and polarity. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol CLDN1.\u003c\/p\u003e\n\u003ch2\u003eResearch Context\u003c\/h2\u003e\n\u003cp\u003eShifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Time course design can be decisive when regulation is transient or compartment dependent. It can be informative in studies that track epithelial differentiation, polarity shifts, or junction remodeling.\u003c\/p\u003e\n\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. This matters because epitope exposure and background can vary with preparation and extraction steps. Include controls that separate true target shifts from matrix or preparation effects.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Claudin-1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Claudin-1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eIntegrate the fixed-section version into your design so Claudin-1 signals can be interpreted alongside matched controls.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102386884953,"sku":"00201-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102386917721,"sku":"00201-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102386950489,"sku":"00201-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102386983257,"sku":"00201-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102387016025,"sku":"00201-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102387048793,"sku":"00201-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn1-colon-ns-new_f822e4cb-2aa4-428a-a9d0-f7b3680947d8.jpg?v=1779283298","url":"https:\/\/absource.de\/products\/claudin-1-cldn1-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}