{"product_id":"claudin-14-cldn14-antibody-ffpe-validated","title":"Claudin-14 (CLDN14) Antibody - FFPE Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eWhen you need to evaluate Claudin-14 (CLDN14) with attention to cellular organization, this antibody provides a focused option. Claudin-14 is a contact-site protein that shapes barrier properties and signaling at the cell surface. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol CLDN14.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eJunction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.\u003c\/p\u003e\n\u003cp\u003eTarget-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Claudin-14 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Claudin-14 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eAs you refine hypotheses around Claudin-14 (CLDN14), the fixed-section format helps keep conclusions tied to preparation context.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102334292313,"sku":"00214-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102334325081,"sku":"00214-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102334357849,"sku":"00214-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102334390617,"sku":"00214-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102334423385,"sku":"00214-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102334456153,"sku":"00214-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cld14-inner-ear-e19_0b776a15-a70f-463c-9d16-2fbd277f9b4f.jpg?v=1779283213","url":"https:\/\/absource.de\/products\/claudin-14-cldn14-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}