{"product_id":"claudin-18-a2-ecl-cldn18-a2-ecl-antibody-western-blot-validated","title":"Claudin-18.a2 ECL (CLDN18.a2-ECL) Antibody - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eThis antibody supports experimental designs that explore Claudin-18.a2 ECL with interpretable controls and clear contrasts. Claudin-18.a2 ECL is a contact-site protein that shapes barrier properties and signaling at the cell surface. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eFollowing Claudin-18.a2 ECL across perturbations can help separate expression effects from compartment shifts.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eResearchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eIn practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy. In oncology research models, expression shifts can accompany changes in adhesion, signaling, or differentiation state.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eWhen samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.\u003c\/p\u003e\n\u003cp\u003eThe denaturing-format format fits designs where Claudin-18.a2 ECL is evaluated with deliberate controls and careful comparisons.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102300016985,"sku":"00218.2ECL-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102300049753,"sku":"00218.2ECL-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102300082521,"sku":"00218.2ECL-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102300115289,"sku":"00218.2ECL-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102300148057,"sku":"00218.2ECL-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102300180825,"sku":"00218.2ECL-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn18a1a2skinimage.jpg?v=1779283159","url":"https:\/\/absource.de\/products\/claudin-18-a2-ecl-cldn18-a2-ecl-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}