{"product_id":"claudin-18-cldn18-human-antibody-ffpe-validated","title":"Claudin-18 (CLDN18) (Human) Antibody - FFPE Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eThis antibody is suited for researchers who want to evaluate Claudin-18 (CLDN18) and relate it to cell-state biology. Claudin-18 is a membrane-associated component that helps organize cell-cell contacts and polarity. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eMonitoring Claudin-18 alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eIn cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.\u003c\/p\u003e\n\u003cp\u003eWhen cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eIn sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Claudin-18 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Claudin-18 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section version supports deeper biological narratives around Claudin-18 (CLDN18) without overcomplicating setup.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102299525465,"sku":"00218H-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102299558233,"sku":"00218H-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102299591001,"sku":"00218H-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102299623769,"sku":"00218H-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102299656537,"sku":"00218H-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102299689305,"sku":"00218H-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn18-human_d95c2fa3-829d-4791-b227-008fe4152950.jpg?v=1779283156","url":"https:\/\/absource.de\/products\/claudin-18-cldn18-human-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}