{"product_id":"claudin-2-cldn2-monoclonal-antibody-e5-clone-western-blot-validated","title":"Claudin-2 (CLDN2) Monoclonal Antibody (E5 Clone) - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eThis antibody enables you to evaluate Claudin-2 with a direct, biology-first readout. Claudin-2 is a contact-site protein that shapes barrier properties and signaling at the cell surface. Focus on trends across conditions rather than single-point snapshots.\u003c\/p\u003e\n\u003cp\u003eTracking Claudin-2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eResearchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eTarget-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eThis denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Claudin-2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Claudin-2 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eChoose the denaturing-format option when you want Claudin-2 results aligned to your sample format.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102384132441,"sku":"00202E5-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102384165209,"sku":"00202E5-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102384197977,"sku":"00202E5-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102384230745,"sku":"00202E5-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102384263513,"sku":"00202E5-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102384296281,"sku":"00202E5-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/screen-shot-2022-07-13-at-11.18.24-am.png?v=1779283288","url":"https:\/\/absource.de\/products\/claudin-2-cldn2-monoclonal-antibody-e5-clone-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}